Normal interaction of plasma retinol-binding protein from retinitis pigmentosa with bovine pigment epithelium.

Investigative ophthalmology Pub Date : 1976-12-01
G Maraini, F Gozzoli
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Abstract

The interaction between retinol-binding protein and normal bovine pigment epithelium has been studied with the use of iodinated retinol-binding protein isolated from the plasma of patients with the recessive form of retinitis pigmentosa and of normal subjects. It is concluded that the capacity of the plasma carrier protein to interact with the retinol-binding protein receptor of bovine pigment epithelium is unimpaired in retinitis pigmentosa with autosomal recessive inheritance.

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视网膜色素变性血浆视黄醇结合蛋白与牛色素上皮的正常相互作用。
利用从隐性色素性视网膜炎患者和正常人血浆中分离的碘化视黄醇结合蛋白,研究了视黄醇结合蛋白与正常牛色素上皮之间的相互作用。由此可见,在常染色体隐性遗传的视网膜色素变性患者中,血浆载体蛋白与牛色素上皮视黄醇结合蛋白受体相互作用的能力未受损害。
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