Improving relaxant effect of contracted airway smooth muscles

A. Al-Jumaily, M. Mathur
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Abstract

Treatments for asthma are largely pharmaceutical, with some therapies also utilizing alternative breathing techniques. The objective of both medical and alternative methods is to relax contracted airway smooth muscle (ASM). As a means of investigating more-effective alternative treatment methods for contracted airways, we analyze the combined effects of bronchodilators and length oscillations on isolated, contracted ASM. This work suggests that relaxation of isolated, contracted ASM is enhanced by combining oscillations with pharmaceutical relaxant.
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改善气道平滑肌收缩的松弛效果
哮喘的治疗主要是药物治疗,一些治疗方法也使用替代呼吸技术。医学和替代方法的目的都是放松收缩的气道平滑肌(ASM)。作为研究气道收缩更有效的替代治疗方法的一种手段,我们分析了支气管扩张剂和长度振荡对孤立的,收缩的ASM的联合作用。这项工作表明,通过将振荡与药物松弛剂结合,孤立的收缩的ASM的松弛得到增强。
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