Towards a Polio free World – the End Game Plan

Dipankar Mukherjee
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Abstract

Poliomyelitis, the dreaded cause of lameness, was ravaging the world in 1988; when more than 125 countries were endemic with the disease and about 350,000 new cases were reported every year. It could have been fanciful to consider eradicating the disease in any future. It was a resolve bold enough at the 41st World Health Assembly then to do it. The disease did provide epidemiological opportunities to make it a possible candidate for eradication and the idea was first realized soon in 1997; when the American region was certified as polio free; the last case being reported from Peru in 1994 (Louis Fermin Tenorio). Other regions did not fall short much; Mum Chanty of Cambodia was the last case from Western Pacific region in 1997 and the region was certified as polio free subsequently in the year 2000. Europe was the third region in the list; Melik Minas from Turkey had the disease in 1999; and the region got the same certificate in 2002.Meanwhile the story in India and South East Asian region was more protracted. Of the three types of polio viruses, the weakest one, wild type 2 was reported last from Aligarh in India in 1999. But it took another thirteen years to put a stop to the next type, wild type 3 (Pakistan in 2012). The last wild polio virus case of India and South East Asia region (onset on January 13) was found at Howrah in 2011 when poor Ruksar Khatun had contacted the disease. In 2012 India was declared no longer a polio endemic country. Later on the South East Asian region was certified as polio free on March 27, 2014. But in Africa and two countries of Eastern Mediterranean region ( Pakistan and Afghanistan ) transmission of wild polio virus continued. On July 24, 2014 last wild polio virus of Africa was detected in Nigeria. Subsequently the country interrupted wild polio virus transmission and was declared non endemic in 2015 leaving only two countries from the 125 when the journey had started. The latest of such glorious milestones was achieved when WHO certified that type 2 wild polio virus has been eradicated on September 20, 2015. The success story in India has been lauded greatly by the international community as technically speaking; the scenario had been most challenging in this country. But elsewhere, like in Afghanistan and Nigeria, things still pose problem – a huge number of children are still unreachable and the health workers being targeted with physical assaults even in 2012 and 2013.
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迈向无脊髓灰质炎世界——终极行动计划
1988年,可怕的致残原因——脊髓灰质炎肆虐全球;当时有超过125个国家流行这种疾病,每年报告的新病例约为35万例。考虑在将来根除这种疾病可能是异想天开。在当时的第41届世界卫生大会上,这是一个足够大胆的决心。这种疾病确实提供了流行病学机会,使其成为根除的可能候选者,这一想法很快在1997年首次实现;当美洲地区被认证为无脊髓灰质炎时;秘鲁最后一例报告于1994年(Louis Fermin Tenorio)。其他地区的差距并不大;柬埔寨的Mum Chanty是1997年西太平洋区域的最后一例病例,该区域随后于2000年被认证为无脊髓灰质炎。欧洲是榜单上的第三个地区;1999年,土耳其的梅利克·米纳斯患上了这种疾病;该地区在2002年获得了同样的证书。与此同时,印度和东南亚地区的故事则更为漫长。在三种类型的脊髓灰质炎病毒中,最弱的一种是1999年在印度阿利格尔报告的野生2型。但又花了13年的时间才阻止了下一种类型,野生型3(2012年在巴基斯坦)。印度和东南亚地区最后一例野生脊髓灰质炎病毒病例(发病于1月13日)是2011年在豪拉发现的,当时贫穷的Ruksar Khatun接触了这种疾病。2012年,印度被宣布不再是脊髓灰质炎流行国家。随后,东南亚地区于2014年3月27日被认证为无脊髓灰质炎。但在非洲和东地中海区域的两个国家(巴基斯坦和阿富汗),野生脊髓灰质炎病毒的传播仍在继续。2014年7月24日,尼日利亚发现了非洲最后一种野生脊髓灰质炎病毒。随后,该国中断了脊髓灰质炎病毒的野生传播,并于2015年被宣布为非流行国家,在开始这一旅程时,125个国家中只有两个国家。世卫组织于2015年9月20日证实2型野生脊髓灰质炎病毒已被根除,这是这一光荣里程碑的最新成就。从技术上讲,印度的成功故事受到了国际社会的高度赞扬;这种情况在这个国家是最具挑战性的。但在其他地方,如阿富汗和尼日利亚,情况仍然存在问题——大量儿童仍然无法接触到,卫生工作者甚至在2012年和2013年都成为人身攻击的目标。
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