Medulloblastoma : A Common Pediatric Malignancy

B. Saberi
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Abstract

Medulloblastoma arises from the fourth ventricle’s roof of the brain. It is the most common primitive neuroectodermal tumor and is one of the most common pediatric malignancies. It’s male to female ratio is about two to one. Arising from the forth ventricle’s roof, causes tumor to develop hydrocephalus. Complete resection of the tumor in case of presence of the brainstem invasions is impossible. At the time of diagnosis, investigation for metastasis should be done since about ten to thirty-five percent of the cases have shown some degrees of metastasis once they have been diagnosed [1-4]. Medulloblastoma comprises about fifteen to twenty percent of the intracranial tumors in the pediatric groups. The first decade of life is the peak time for medulloblastoma appearance.
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髓母细胞瘤:一种常见的儿科恶性肿瘤
髓母细胞瘤起源于大脑第四脑室顶部。它是最常见的原始神经外胚层肿瘤,是最常见的儿童恶性肿瘤之一。男女比例大约是2:1。起源于第四脑室顶部,导致肿瘤发展为脑积水。在脑干侵犯的情况下,完全切除肿瘤是不可能的。在诊断时,应检查是否有转移,因为大约10%至35%的病例在确诊后会出现一定程度的转移[1-4]。髓母细胞瘤占儿科颅内肿瘤的15%到20%。生命的前十年是成神经管细胞瘤出现的高峰期。
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