Role of pH in the Mutagenicity of Aflatoxin B1 in Maize Tortillas during In Vitro HumanDigestion Model

María de Guadalupe Moctezuma-Zárate, M. Carvajal-Moreno, J. Espinosa-Aguirre, Maria Eugenia Gonsebatt-Bonaparte, F. Rojo-Callejas, Pavel Castillo-Urueta Israel Perez-Lopez, S. Ruiz-Velasco
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引用次数: 13

Abstract

Role of pH in the Mutagenicity of Aflatoxin B1 in Maize Tortillas during In Vitro Human Digestion Model Aflatoxins (AFs) are potent mutagens, carcinogens and teratogens for humans; thus their presence in food is of great concern. A maize tortilla survey in Mexico revealed that 17% are contaminated with AFs. The initial process to prepare tortillas includes boiling maize grains with lime and to assumpt that AFs in maize tortillas are destroyed, protecting consumers from their mutagenic effects.The purpose of this study was to investigate the mutagenicity of aflatoxin B1 (AFB1) in tortillas during digestion.
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体外人消化模型中pH对玉米玉米饼中黄曲霉毒素B1致突变性的影响
黄曲霉毒素(AFs)是人类的强诱变剂、致癌物和致畸物。因此,它们在食物中的存在是非常值得关注的。墨西哥的一项玉米饼调查显示,17%的玉米饼被AFs污染。准备玉米饼的最初过程包括用石灰煮玉米谷物,并假设玉米饼中的AFs被破坏,保护消费者免受其诱变作用。本研究的目的是研究黄曲霉毒素B1 (AFB1)在玉米饼消化过程中的诱变性。
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