Non-Operative Treatment of Tibial Tubercle Fractures: Who is at Risk for Failure?

Lauren Spirov, Konstantin Brnjoš, N. Kaushal, F. Edobor-Osula, Alexander Griffith, J. Blanco, Clare Kehoe, J. Schlechter, Evelyn S. Thomas, Lindsay M. Crawford, Abhi Rashiwala, D. Greenhill, Haley N Tornberg, B. Williams, Kevin Huang, Neeraj M. Patel
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Abstract

Introduction: Given the relative rarity of tibial tubercle fractures and the high proportion that undergo surgical treatment, there is little data on non-operative management of these injuries. Some patients that are initially treated non-surgically may ultimately require operative intervention. The purpose of this study was to identify risk factors for failed non-operative management of tibial tubercle fractures. Methods: This retrospective comparative study included patients younger than 18 years that underwent initial non-operative treatment of a tibial tubercle fracture at six tertiary children’s hospitals. Those that underwent primary surgical intervention were excluded. Demographic, radiographic, and clinical data were reviewed. Conversion to surgical fixation was considered a failure of non-operative treatment. Univariable analysis was followed by multivariate regression to adjust for confounders. Results: A total of 136 patients were included, of which 19.1% failed non-operative treatment and subsequently underwent surgery. The median age of patients that ultimately required surgery was 14.0 y [IQR (interquartile range) 2.5 y] compared to 12.0 y (IQR 2.0 y) for those that were successfully managed without surgery. Non-operative treatment failed in 7.8% of Ogden type I fractures, 66.7% of type II, 81.8% of type III, 35.7% of type IV, and 7.1% of type V (p<0.001). After adjusting for confounders, including weight and initial weight-bearing status, each year of increasing age raised the odds of failure by 1.9 (95% CI 1.2-3.0, p=0.006). Additionally, Ogden type II fractures had 23.4 times higher odds than type I (95% CI 2.1-260.8, p=0.01). Ogden type III fractures had 36.3 times higher odds of failing non-operative treatment than type I (95% CI 4.2-315.4, p=0.001). Conclusion: In this study of patients with a tibial tubercle fracture initially treated non-operatively, 19.1% ultimately underwent surgery. Increasing age and Ogden type II and III fracture classification were associated with failure of non-operative management. These results may help guide decision-making regarding surgical versus non-surgical treatment. Significance: There is little data on non-operative treatment of tibial tubercle fractures. This study identifies risk factors for failure of non-operative treatment and may aid clinical decision-making.
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胫骨结节骨折的非手术治疗:谁有失败的风险?
引言:由于胫骨结节骨折相对罕见,且接受手术治疗的比例很高,因此关于这些损伤的非手术治疗的数据很少。一些最初非手术治疗的患者最终可能需要手术干预。本研究的目的是确定胫骨结节骨折非手术治疗失败的危险因素。方法:本回顾性比较研究纳入了6所三级儿童医院18岁以下首次接受胫骨结节骨折非手术治疗的患者。那些接受了初次手术干预的患者被排除在外。回顾了人口统计学、放射学和临床资料。转换为手术固定被认为是非手术治疗的失败。单变量分析后进行多变量回归以调整混杂因素。结果:共纳入136例患者,其中19.1%的患者非手术治疗失败后接受手术治疗。最终需要手术的患者的中位年龄为14.0 y [IQR(四分位间距)2.5 y],而未手术成功的患者的中位年龄为12.0 y (IQR 2.0 y)。非手术治疗失败率分别为7.8%、66.7%、81.8%、35.7%、7.1% (p<0.001)。在调整混杂因素(包括体重和初始负重状态)后,年龄每增加一年,失败的几率增加1.9 (95% CI 1.2-3.0, p=0.006)。此外,Ogden II型骨折的发生率是I型骨折的23.4倍(95% CI 2.1 ~ 260.8, p=0.01)。Ogden III型骨折非手术治疗失败的几率是I型骨折的36.3倍(95% CI 4.2-315.4, p=0.001)。结论:在本研究中,最初非手术治疗的胫骨结节骨折患者中,19.1%最终接受手术治疗。年龄的增加和Ogden II型和III型骨折的分类与非手术治疗的失败有关。这些结果可能有助于指导手术与非手术治疗的决策。意义:关于胫骨结节骨折非手术治疗的资料很少。本研究确定了非手术治疗失败的危险因素,可能有助于临床决策。
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