Image guided complex dose delivery for small animal radiotherapy

Mohammad Matinfar, S. Iyer, E. Ford, J. Wong, P. Kazanzides
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引用次数: 6

Abstract

The purpose of the Small Animal Radiation Research Platform (SARRP) is to demonstrate computed tomography, conformal irradiation, and treatment planning capabilities for small animals. The SARRP is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper describes the utilization of the precision radiation beam on the SARRP for “dose painting” complex structures in the mouse brain. Pencil beam dose painting aims to target the tumor as accurately as possible and give it the highest dose of radiation while sparing normal tissue as much as possible.
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小动物放射治疗的图像引导复合给药
小动物辐射研究平台(SARRP)的目的是展示小动物的计算机断层扫描、适形辐射和治疗计划能力。SARRP是一种便携式精确辐射系统,其光束尺寸可小至约0.5 mm,并通过机载锥束CT (CBCT)制导进行最佳规划辐射。本文介绍了利用精确辐射束在SARRP上对小鼠脑内复杂结构进行“剂量绘画”的方法。铅笔束剂量描画的目的是尽可能准确地瞄准肿瘤,在尽可能保留正常组织的同时给予最高剂量的辐射。
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