Mohammad Matinfar, S. Iyer, E. Ford, J. Wong, P. Kazanzides
{"title":"Image guided complex dose delivery for small animal radiotherapy","authors":"Mohammad Matinfar, S. Iyer, E. Ford, J. Wong, P. Kazanzides","doi":"10.1109/ISBI.2009.5193287","DOIUrl":null,"url":null,"abstract":"The purpose of the Small Animal Radiation Research Platform (SARRP) is to demonstrate computed tomography, conformal irradiation, and treatment planning capabilities for small animals. The SARRP is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper describes the utilization of the precision radiation beam on the SARRP for “dose painting” complex structures in the mouse brain. Pencil beam dose painting aims to target the tumor as accurately as possible and give it the highest dose of radiation while sparing normal tissue as much as possible.","PeriodicalId":272938,"journal":{"name":"2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","volume":"19 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2009-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ISBI.2009.5193287","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 6
Abstract
The purpose of the Small Animal Radiation Research Platform (SARRP) is to demonstrate computed tomography, conformal irradiation, and treatment planning capabilities for small animals. The SARRP is a portable system for precision irradiation with beam sizes down to approximately 0.5 mm and optimally planned radiation with on-board cone-beam CT (CBCT) guidance. This paper describes the utilization of the precision radiation beam on the SARRP for “dose painting” complex structures in the mouse brain. Pencil beam dose painting aims to target the tumor as accurately as possible and give it the highest dose of radiation while sparing normal tissue as much as possible.