Retinal findings in chronic kidney disease patients on hemodialysis

R. Hagag, Shimaa El-attar, Waleed A Elrefaey, Amin E Nawar, Nashwa El gharbawy
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Abstract

Background Chronic kidney disease (CKD) is an irreversible condition that leads to progression to end-stage renal disease that requires hemodialysis or kidney transplantation for patient survival and these patients are at risk of developing many complications. In the present study, the retinal findings in CKD patients on hemodialysis are evaluated. Patients and methods This is a cross-sectional noninterventional study that was carried out on CKD patients on hemodialysis for at least 3 months in the Nephrology Unit, Tanta University, Egypt; 160 eyes of 80 patients were included over 6 months. A complete ophthalmic evaluation was performed. Color fundus and spectral domain optical coherence tomography were performed at presentation. Results The visual acuity ranged from 6/6 to 6/18 in 80 eyes, which represents 50%, from 6/24 to 6/60 in 62 eyes, which represents 38.75%, and from less than 6/60 to perception of light in 18 eyes, which represents 11.25%. Fundus examination revealed that eight eyes were normal (5%). Hypertensive retinal changes occurred in 82 eyes with variable degrees of retinopathy. Diabetic retinopathy was found in 30 (18.75%) eyes and macular degeneration was detected in 20 (12.5%) eyes. Retinal vasculitis occurred in two (1.25%) eyes, branch retinal vein occlusion was detected in six (3.75%) eyes, glaucomatous optic neuropathy was found in eight (5%) eyes and central retinal artery occlusion occurred in four (2.5%) eyes. Conclusion The most common visual problems in hemodialysis patients that lead to visual loss are hypertensive and diabetic retinopathy. Hence, it is mandatory to screen fundus changes in CKD to prevent loss of vision.
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慢性肾病血液透析患者的视网膜表现
慢性肾脏疾病(CKD)是一种不可逆的疾病,可导致进展为终末期肾脏疾病,需要血液透析或肾移植才能生存,这些患者有发生许多并发症的风险。在本研究中,对CKD血液透析患者的视网膜检查结果进行了评估。患者和方法这是一项横断面非介入性研究,在埃及坦塔大学肾内科对血液透析至少3个月的CKD患者进行了研究;80例患者160只眼6个月。进行了完整的眼科评估。彩色眼底和光谱域光学相干断层扫描。结果80只眼视力在6/6 ~ 6/18之间,占50%;62只眼视力在6/24 ~ 6/60之间,占38.75%;18只眼视力在6/60以下,占11.25%。眼底检查显示8只眼正常(5%)。高血压性视网膜改变发生在82只不同程度视网膜病变的眼睛。糖尿病视网膜病变30眼(18.75%),黄斑变性20眼(12.5%)。视网膜血管炎2例(1.25%),视网膜分支静脉闭塞6例(3.75%),青光眼视神经病变8例(5%),视网膜中央动脉闭塞4例(2.5%)。结论高血压和糖尿病性视网膜病变是血透患者最常见的视力问题。因此,筛查慢性肾病患者的眼底变化以防止视力丧失是必要的。
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