Analysis of sympathetic nerve activity by power spectrum of arterial pressure fluctuations: effects of salt-induced hypertension and calcium supplementation in rats

K. Ju, T. Kuwaki, A. Ono, T. Tujita, M. Kumada
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Abstract

In salt-loaded or calcium supplied young spontaneously hypertensive rats (SHR), the power spectrum of arterial blood pressure (ABP) was determined in the anesthetized state by forward and backward autoregressive (F-B AR) algorithms. The authors found that salt-loading led to sympathetic overactivity, which was prevented by calcium supplementation, and concluded that F-B AR power spectral analysis of ABP fluctuations in SHR was a useful tool to monitor effects of salt-induced hypertension and calcium supplementation.
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用动脉压波动功率谱分析交感神经活动:盐致高血压和补钙对大鼠的影响
采用前向和后向自回归(F-B AR)算法测定麻醉状态下自发性高血压幼鼠(SHR)动脉血压(ABP)功率谱。作者发现,盐负荷导致交感神经过度活跃,而补钙可以预防这种情况,并得出结论,对SHR中ABP波动的F-B AR功率谱分析是监测盐诱导高血压和补钙影响的有用工具。
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