A Case of Secondary Syphilis with Inflammation of Oral Mucosa

Atsushi Uesugi, Fumihiko Tsushima, Risa Shimizu, Chisato Nakagawa, Kiyoshi Sato, J. Sakurai, H. Harada
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Abstract

: We experienced a case of secondary syphilis with inflammation of the oral mucosa. The patient was a 24-year-old woman who was referred to our department with chief complaints of healing failure of stomatitis in the oral cavity. Ulcers were found in the tongue and palate, and findings of angina were observed. Both the qualitative and quantitative values of TPHA and RPR were positive. Biopsy from the palate showed positive immunohistochemical staining with anti Treponema pallidam antibody. Flat condyloma was also recognized and diagnosed as secondary syphilis. Ampicillin was administered and the lesion disappeared. Because syphilis is preceded by oral lesions, early detection is important.
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继发性梅毒伴口腔黏膜炎症1例
我们报告了一例伴口腔黏膜炎症的二期梅毒患者。患者为24岁女性,以口腔炎愈合失败主诉转介至我科。在舌头和上颚发现溃疡,并观察心绞痛的表现。TPHA和RPR的定性和定量结果均为阳性。上颚活检显示抗梅毒螺旋体抗体免疫组化染色阳性。扁平尖锐湿疣也被诊断为继发性梅毒。给予氨苄西林后病变消失。由于梅毒发生前会出现口腔病变,因此早期发现非常重要。
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