Role of Intraoperative Transesophageal Echocardiography in the Management of Renal Cell Carcinoma with Cavoatrial Extension

S. Negi, G. Munirathinam, G. Puri, K. Gourav, S. Niyogi, Vamsi Dar
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Abstract

In all, 4–10% of tumor thrombus in renal cell carcinoma (RCC) extends into the inferior vena cava (IVC). When the thrombus extends into the right atrium (RA), it becomes surgically challenging; and depending on its extension and adherence to the underlying structure, it may need cardiopulmonary bypass (CPB). The utility of transesophageal echocardiography (TEE) is reviewed for the management of RCC with cavoatrial extension. Intraoperative TEE is an essential modality in cases of RCC with level IV tumor thrombus, and in cases that require CPB with or without deep hypothermic circulatory arrest (DHCA). Intraoperative TEE provides us real-time information about thrombus staging in addition to the properties of the thrombus, such as adherence and fragility. Intraoperative TEE can also be used to assess cardiac function, fluid status, real-time monitoring of thrombus including embolization while manipulation and to ensure no residual thrombus. We therefore recommend the use of intraoperative TEE in RCC with level IV tumor thrombus. In the future, more research is needed to demonstrate the impact of intraoperative TEE on morbidity, mortality, and complication rate of the procedures.
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术中经食管超声心动图在肾细胞癌伴腔房扩张的治疗中的作用
总的来说,4-10%的肾细胞癌(RCC)的肿瘤血栓延伸到下腔静脉(IVC)。当血栓延伸到右心房(RA)时,它就变得具有手术挑战性;根据它的延伸和对底层结构的粘附,它可能需要体外循环(CPB)。本文综述了经食管超声心动图(TEE)在肾细胞癌伴腔房扩张的治疗中的应用。术中TEE是伴有IV级肿瘤血栓的RCC,以及需要CPB伴或不伴深度低温循环停搏(DHCA)的病例的基本模式。术中TEE为我们提供了关于血栓分期的实时信息,以及血栓的特性,如粘附性和易碎性。术中TEE还可用于评估心功能、体液状态,实时监测血栓,包括操作时栓塞,并确保无残留血栓。因此,我们推荐术中TEE用于有IV级肿瘤血栓的RCC。在未来,需要更多的研究来证明术中TEE对手术的发病率、死亡率和并发症发生率的影响。
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