{"title":"Investigations into the inhibition of DNA repair processes by detergents.","authors":"H Tuschi, W Klein, F Kocsis, E Bernat, H Altmann","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The inhibition of semi-conservative DNA replication and unscheduled DNA synthesis by three different detergents was investigated in mouse spleen cells. The investigations were made by following the kinetics of the incorporation of 3H-thymidine into the DNA, as well as by autoradiographic studies. At various concentrations different inhibition patterns were found and the significance of these findings is discussed.</p>","PeriodicalId":75826,"journal":{"name":"Environmental physiology & biochemistry","volume":"5 2","pages":"84-91"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Environmental physiology & biochemistry","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The inhibition of semi-conservative DNA replication and unscheduled DNA synthesis by three different detergents was investigated in mouse spleen cells. The investigations were made by following the kinetics of the incorporation of 3H-thymidine into the DNA, as well as by autoradiographic studies. At various concentrations different inhibition patterns were found and the significance of these findings is discussed.
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