Skrining Fitokimia Hasil Ekstraksi Bertingkat Daun Jengkol (Archidendron jiringa) dan Aplikasinya Sebagai Zat Antijamur

Mohammad Jihad Madiabu, Ilyas Taufik Abdul Aziz, S. Supriyono, Ariefiangga Pratama Putra, Anom Cahyotomo, Hanum Sekar Panglipur
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Abstract

Phytochemical screening and antifungal activity test of jengkol leaf (Archidendron jiringa) extract have been carried out. The purpose of this research is determine secondary metabolite content and antifungal activities of jengkol leaf extract. Extraction of jengkol leaf was conducted with sequential extraction technique with various solvent such as hexane, ethyl acetate and methanol respectively. FTIR characterization of jengkol leaf extract show the presence of O-H, C-H C-O and C=O groups. Based on phytochemical sceening test, jengkol leaf extract contains phenolic, flavonoid, tannin, sterol, and alkaloid compound. Antifungal test was investigated on Candida albicans by disc diffusion methods. Jengkol leaf extract that was obtained from methanol extraction show inhibiton zone to Candida albicans of (1,42 ± 0,16) mm, while extraction with ethyl acetate and hexane aren’t show inhibition zone. Antifungal test result showed that jengkol leaf extract has potential as antifungal agent
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对植物化学物质进行筛选,提取出多层的葛缕叶(Archidendron jiringa)和用作抗真菌材料的应用
对荆芥叶提取物进行了植物化学筛选和抗真菌活性试验。本研究的目的是测定荆芥叶提取物的次生代谢物含量和抗真菌活性。采用正己烷、乙酸乙酯、甲醇等不同溶剂,采用序贯提取法提取丁香叶。通过FTIR表征,丁香叶提取物中存在O- h、C- h、C-O和C=O基团。经植物化学筛选,丁香叶提取物含有酚类、类黄酮、单宁、甾醇和生物碱化合物。采用圆盘扩散法对白色念珠菌进行抑菌试验。甲醇提取的荆芥叶提取物对白色念珠菌有(1,42±0,16)mm的抑制区,而乙酸乙酯和己烷提取的荆芥叶提取物对白色念珠菌无抑制区。抑菌试验结果表明,荆芥叶提取物具有潜在的抑菌作用
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