Kidney Tumors in Children

Şefika Akyol
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Abstract

Wilms tumor (WT) is an embryonal tumor of the kidneys. It is associated with many oncogenic genetic aberrations and congenital anomalies. Owing to worldwide clinical research and optimized patient care, curative therapy can be obtained in 90% of diagnosed children with WT. The decision of treatment mainly depends on stage, age, histological type, and genetic markers. Except for WT; congenital mesoblastic nephroma, clear cell sarcoma, malignant rhabdoid tumor, and renal cell carcinoma constitute 5% of kidney tumors. Herein, WT and other tumors of the kidney will be emphasized.
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儿童肾脏肿瘤
肾母细胞瘤(WT)是一种肾脏胚胎性肿瘤。它与许多致癌基因畸变和先天性异常有关。由于世界范围内的临床研究和优化的患者护理,90%确诊的WT患儿可以获得根治性治疗。治疗的决定主要取决于分期、年龄、组织学类型和遗传标记。除了WT;先天性间母细胞肾瘤、透明细胞肉瘤、恶性横纹肌瘤和肾细胞癌占肾肿瘤的5%。在这里,WT和其他肾脏肿瘤将被强调。
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