Diagnostic Accuracy of Recognition of Stroke in Emergency Room Score in Patients with Ischemic Stroke

S. M. Shah, Zamir Butt, Muhammad Afzal, S. Tarar, S. Talat
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Abstract

To determine the diagnostic accuracy of ROSIER scale in patients with ischemic stroke taking non-enhanced CT scan brain as gold standard. Materials and Methods: Cross-sectional study conducted at tertiary care hospital in Gujrat from October 2019 to December 2020. Patients of both sex groups aged 30- 75 years presented in emergency within 24 hours of onset of focal neurological deficit which is objectively present and suspected of ischemic stroke. 289 patients were included. Patient history and neurological examination done calculating ROSIER scale and ischemic stroke diagnosed after CT scan brain done 24 hours after onset of symptoms. Sensitivity, specificity, PPV, NPV and diagnostic accuracy of ROSIER scale were calculated. Data analysis was done using SPSS 20.0. Results: In this study group 141(48.8%) were male while 148(51.2%) were female. Mean age was 62.1+11.02 years. 49(17%) patients were aged <50 years while 240(83%) were aged >50 years. 215(74.4%) presented within 12 hours while 74(25.6%) after 12 hours of symptoms onset. Sensitivity of ROSIER scale for diagnosing ischemic stroke was 98.86%(95%CI;95.96%-99.86%), specificity 5.31%(95%CI;1.97%-11.20%), PPV 61.92%(95% CI;60.82%-63.01%) and NPV was 75%(95%CI;38.13%-93.59%). LR+ was 1.04(95%CI; 1.00-1.09) while LR- was 0.21(95%CI; 0.04-1.04). Conclusion: ROSIER score can be used as initial screening test in patients with stroke. It has high sensitivity but low specificity and is a good test to rule in and rule out stroke patients.
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缺血性脑卒中患者急诊室评分识别脑卒中的诊断准确性
以脑CT非增强扫描为金标准,确定ROSIER量表对缺血性脑卒中的诊断准确性。材料与方法:2019年10月至2020年12月在古吉拉特邦三级保健医院进行的横断面研究。年龄30- 75岁的男女患者均在发病24小时内出现局灶性神经功能缺损,客观存在并怀疑为缺血性脑卒中。共纳入289例患者。患者病史和神经系统检查,计算ROSIER量表,并在症状出现24小时后进行脑CT扫描诊断缺血性卒中。计算ROSIER量表的敏感性、特异性、PPV、NPV及诊断准确率。数据分析采用SPSS 20.0软件。结果:本组患者中男性141例(48.8%),女性148例(51.2%)。平均年龄62.1+11.02岁。49例(17%)患者年龄在50岁。215例(74.4%)在12小时内出现,74例(25.6%)在12小时后出现。ROSIER量表诊断缺血性脑卒中的灵敏度为98.86%(95%CI;95.96% ~ 99.86%),特异性为5.31%(95%CI;1.97% ~ 11.20%), PPV为61.92%(95% CI;60.82% ~ 63.01%), NPV为75%(95%CI;38.13% ~ 93.59%)。LR+为1.04(95%CI;1.00-1.09), LR-为0.21(95%CI;0.04 - -1.04)。结论:ROSIER评分可作为脑卒中患者的初步筛查指标。它灵敏度高,但特异性低,是诊断和排除脑卒中患者的好方法。
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