{"title":"Effect of different sedative drugs on the proliferation of bone marrow cells. Preliminary results.","authors":"C Dresch, O Poirier, J Minc, C Bismuth","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Several drugs were assayed for their effect on bone marrow hematopoïetic cells proliferation. Chlorpromazine, barbiturates and benzopiperidine were found active only at toxic dosage. Propranolol and fluanison seem in the preliminary studies to lessen 3 H-thymidine incorporation in vitro at non toxic concentration.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"8 4","pages":"252-7"},"PeriodicalIF":0.0000,"publicationDate":"1975-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Several drugs were assayed for their effect on bone marrow hematopoïetic cells proliferation. Chlorpromazine, barbiturates and benzopiperidine were found active only at toxic dosage. Propranolol and fluanison seem in the preliminary studies to lessen 3 H-thymidine incorporation in vitro at non toxic concentration.
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