Toomoo Fujisawa, A. Inui, H. Komatsu, Y. Miyagawa, M. Onoue
{"title":"Interferon-α Therapy for Children with Chronic Hepatitis C","authors":"Toomoo Fujisawa, A. Inui, H. Komatsu, Y. Miyagawa, M. Onoue","doi":"10.7097/APS.199806.0146","DOIUrl":null,"url":null,"abstract":"We followed 53 children with chronic hepatitis C for more than 3 years. Spontaneous remission occurred only 3 (6%) in whom the serum titer of HCV-RNA was low. We considered interferon (IFN) should be adopted in all children with chronic hepatitis C but those who expected to be remitted spontaneously. We evaluated the effect of IFN therapy on 32 children and investigated factors that may influence the outcome of the treatment. A complete response was obtained in 13 children (41%). IFN was well tolerated.","PeriodicalId":306859,"journal":{"name":"Acta paediatrica sinica","volume":"30 1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1998-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta paediatrica sinica","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7097/APS.199806.0146","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
We followed 53 children with chronic hepatitis C for more than 3 years. Spontaneous remission occurred only 3 (6%) in whom the serum titer of HCV-RNA was low. We considered interferon (IFN) should be adopted in all children with chronic hepatitis C but those who expected to be remitted spontaneously. We evaluated the effect of IFN therapy on 32 children and investigated factors that may influence the outcome of the treatment. A complete response was obtained in 13 children (41%). IFN was well tolerated.
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