Study on Preparation and in Vitro Sustained Release of Bu-Yang-Huan-Wu Sustained-Release Tablet

Yang Yantao , Wu Chunying , Zhou Jin , Shi Jilian , Liu Wenlong , He Fuyuan
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Abstract

Aim of this study was to prepare Bu-Yang-Huan-Wu (BYHW) elementary osmotic pump sustained-release tablets and to investigate the situation of its main effective components of “synchronous control and sustained release.” The releasing similarity of chromatographic fingerprints of BYHW in vitro dissolution was evaluated. The results showed that BYHW elementary osmotic pump sustained-release tablet was prepared and the chromatographic fingerprints were extracted. And data of its release similarity was also obtained. It was concluded that BYHW elementary osmotic pump sustained-release tablet can achieve the synchronous control and sustained release of many ingredient. It is also fit for the characteristic of Chinese herbal medicine compound.

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补阳还阴缓释片的制备及体外缓释研究
本研究的目的是制备补阳环午(BYHW)初级渗透泵缓释片,并考察其主要有效成分的“同步控释”情况。评价了其体外溶出度色谱指纹图谱的释放相似性。结果表明:制备了BYHW初级渗透泵缓释片,并提取了其色谱指纹图谱。并获得了其释放相似度的数据。结果表明,BYHW初级渗透泵缓释片可实现多种成分的同步控制和缓释。该方法也符合中药复方的特点。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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