Cytogenetic investigations on leucocytes of workers from a cadmium plant.

G Deknudt, A Léonard
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Abstract

Chromosome analysis has been performed on workers from a cadmium plant who were exposed to fumes and dust of cadmium and lead. The 35 workers were classified, according to the type and duration of exposure, into a group (cadmium service) exposed to high levels of lead and cadmium in the absence of zinc (23 people) and a group of rolling-mill workers subjected mostly to zinc but also to lower levels of lead and cadmium (12 people). A higher yield of severe chromosome anomalies (chromatid exchange, disturbance of spiralization, chromosome translocation, ring and dicentric chromosomes) together with a total lower number of structural aberrations was observed in the cadmium workers when compared with the rolling-mill group.

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镉植物工蜂白细胞的细胞遗传学研究。
对接触镉和铅的烟雾和粉尘的镉工厂工人进行了染色体分析。根据接触的类型和持续时间,35名工人被分为在没有锌的情况下暴露于高水平铅和镉的一组(镉服务)(23人)和一组主要暴露于锌但也暴露于较低水平铅和镉的轧机工人(12人)。与轧钢组相比,镉工人的严重染色体异常(染色单体交换、螺旋化干扰、染色体易位、环状和双中心染色体)发生率更高,结构畸变总数更少。
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