Depression in Various Ethnic Groups of Pakistan after Primary Percutaneous Coronary Intervention

A. Ali, Khalid Iqbal, Dileep Kumar, T. Sagheer, Suresh Kumar, C. Parkash
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Abstract

Background: Depression is very common among individuals recovering from a chronic illness with long-term or recurrent hospitalization. Post-myocardial infarction patients are at risk of developing depression and is considered to be a risk for elevated mortality. Aims and Objective: To determine the frequency of depression among various ethnic groups of patients post primary percutaneous coronary intervention for acute myocardial infarction. Material and Methods: �A cross-sectional study was conducted at the out-patients department of NICVD, Pakistan for a duration of six months from February 2021 to July 2021. Total 256 patients aged between 18 to 85 years, were diagnosed with STEMI, and had undergone PCI were included in the study. Patients with prior diagnosis of CAD or had prior history of psychological problems were excluded from the study. Patients were interviewed for depression by using Beck's depression inventory (BDI). Patients scoring > 10 were labeled as having depression. Results: Out of 256 patients, 122 (48.8%) patients were screened positive for depressive symptoms.� Out of these, about 21.1% had mild depression, 16% had borderline clinical depression, 10.5% had moderate depression, while about 0.8% had severe depression. Age of 71 years and above, female gender, diabetes, hypertension, and sedentary lifestyle were all significantly correlated with increased risk of depression in post-MI patients with BDI scores of 17.64 � 7.9 (<0.0001), 13.54 � 7.53 (0.015), 14.47 � 7.61 (p<0.0001), 13.52 � 6.83 (p<0.0001), and 16.69 � 7.57 (p<0.0001), respectively. Conclusion: After percutaneous coronary intervention for MI, depression was found in almost half of the patients. However, as per our study, the risk for depression is independent of ethnic background.
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巴基斯坦不同族群经皮冠状动脉介入治疗后的抑郁症
背景:抑郁症在长期或反复住院治疗的慢性疾病恢复期患者中非常常见。心肌梗死后患者有发展为抑郁症的风险,被认为是死亡率升高的风险。目的与目的:了解不同民族急性心肌梗死患者经皮冠状动脉介入治疗后抑郁的发生率。材料和方法:一项横断面研究于2021年2月至2021年7月在巴基斯坦NICVD门诊部进行,为期6个月。研究共纳入256例年龄在18 ~ 85岁之间,诊断为STEMI并接受PCI治疗的患者。先前诊断为CAD或有先前心理问题史的患者被排除在研究之外。采用贝克抑郁量表(BDI)对患者进行抑郁问卷调查。得分大于10分的患者被标记为患有抑郁症。结果:256例患者中,122例(48.8%)患者抑郁症状筛查呈阳性。其中,约21.1%患有轻度抑郁症,16%患有边缘性临床抑郁症,10.5%患有中度抑郁症,约0.8%患有重度抑郁症。BDI评分分别为17.64 ~ 7.9(<0.0001)、13.54 ~ 7.53(0.015)、14.47 ~ 7.61 (p<0.0001)、13.52 ~ 6.83 (p<0.0001)和16.69 ~ 7.57 (p<0.0001)的心肌梗死后患者,年龄71岁及以上、女性、糖尿病、高血压和久坐生活方式均与抑郁风险增加显著相关。结论:心肌梗死经皮冠状动脉介入治疗后,近半数患者出现抑郁症状。然而,根据我们的研究,患抑郁症的风险与种族背景无关。
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