Association of Post-Operative Infection and MI with Metabolic Syndrome after Coronary Artery Bypass Graft

Ghulam Kibriya, A. Abbas, Hina Aftab, M. Akram, Yahya Saeed, Omar Iqbal, A. Iqbal
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Abstract

Objective: To find out association of metabolic syndrome with early outcomes e.g.(post operative infection, acute kidney injury, and MI) after CABG. Study Design: This was a comparative study. Place and Duration: This study was performed from the first of July 2020 to the first of January 2021 at the Cardiac Surgery Department, PIC, Jail Road, Lahore Methodology: This comparative study performed from the first of July 2020 to the first of January 2021 at the Cardiac Surgery Department, PIC, Jail Road, Lahore. The approach of non-probability sampling was applied. After obtaining consent on a consent form, 172 Patients (86 in the exposed group and 86 in the non-exposed group) were included. Results: The average age of the participants in this study was 55.30 ± 8.77 years; there were 130 cases (75.6%) of men and 42 cases (24.4%) of women. There were 56 (65.12%) men and 30 (34.88%) women in the exposed group, compared to 74 (86.05%) men and 12 (13.95%) women in the non-exposed group. Post-operative MI was statistically insignificant in both groups, p-value >0.05, renal failure and postoperative infection were statistically significant. Conclusion: Because many MetS syndrome factors are under our control, it is important to prevent it early especially in cases of CABG, to get better outcomes. Although we noted that renal failure and postoperative infection were statistically high in exposed groups, with a p-value of 0.05, and MI was statistically similar in both groups, with a p-value of >0.05, the outcomes of the current study were quite different and unexpected. Further studies are suggested to be done on a larger scale. Keywords: CABG, Lipid Profile, Diabetes, Obesity, Mortality
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冠状动脉搭桥术后感染和心肌梗死与代谢综合征的关系
目的:探讨代谢综合征与冠脉搭桥术后早期结局(术后感染、急性肾损伤、心肌梗死)的关系。研究设计:这是一项比较研究。地点和时间:本研究于2020年7月1日至2021年1月1日在拉合尔监狱路PIC心脏外科进行。方法:本比较研究于2020年7月1日至2021年1月1日在拉合尔监狱路PIC心脏外科进行。采用了非概率抽样的方法。在获得同意表格后,纳入172名患者(86名暴露组和86名非暴露组)。结果:研究对象平均年龄55.30±8.77岁;男性130例(75.6%),女性42例(24.4%)。暴露组男性56例(65.12%),女性30例(34.88%),未暴露组男性74例(86.05%),女性12例(13.95%)。两组术后心肌梗死差异均无统计学意义,p值>0.05,肾功能衰竭和术后感染差异均有统计学意义。结论:由于met综合征的许多因素都在我们的控制范围内,因此早期预防非常重要,特别是在CABG病例中,以获得更好的效果。虽然我们注意到暴露组肾衰竭和术后感染发生率高,p值为0.05,两组心肌梗死发生率相似,p值为0.05,但本研究结果差异很大,出乎意料。建议进行更大规模的进一步研究。关键词:冠状动脉搭桥,血脂,糖尿病,肥胖,死亡率
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