Structure Modeling and Mechanical Analyses of Meniscal Implants Based on Triply Periodic Minimal Surfaces

Shi Jianping, Zhu Liya, Yang Ji-quan
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Abstract

Extended Abstract As an important part of the knee joint, the meniscus plays a role in transmitting load, absorbing oscillation, and improving joint stability [1]. However, joint disease, degeneration, trauma and other causes may cause damage to the meniscus. Meniscus transplantation can solve diseases such as osteoarthritis caused by meniscus loss, but there are some problems such as limited stent replacement, immune response, and structural mismatch [2, 3]. There is currently a problem of mismatch in mechanical properties between commercial meniscus implants and natural meniscus, which is not conducive to long-term implantation [4]. Therefore, a porous polycarbonate-polyurethane meniscus implant based on a very small threeperiod surface is proposed. First, a 3D model of the knee joint was established based on the CT scan results of the knee joint [5]. The porous element is constructed by Primitive minimal surface. After Boolean operation with the outer meniscus structure, a series of implant structures with different pore sizes or porosity are obtained by adjusting the surface construction parameters. Then, finite element simulation was performed to compare the mechanical changes of articular cartilage and bilateral meniscus in the knee joint of the natural meniscus and the designed porous meniscus. The results show that the use of a porous meniscal implant can effectively reduce the compressive stress and shear stress concentration on the femoral cartilage and the tibial cartilage. At the same time, changes in the structural parameters of the porous implant affect the stress of the articular cartilage. In addition to having good mechanical properties, the structure can also be rapidly formed by three-dimensional printing technology, which provides a new idea for clinical application.
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基于三周期极小曲面的半月板植入体结构建模与力学分析
半月板作为膝关节的重要组成部分,具有传递载荷、吸收震荡、提高关节稳定性的作用[1]。但关节疾病、退行性变、外伤等原因均可引起半月板损伤。半月板移植可以解决半月板丢失引起的骨关节炎等疾病,但存在支架置换受限、免疫应答、结构错配等问题[2,3]。目前商用半月板植入物与天然半月板存在力学性能不匹配的问题,不利于长期植入[4]。因此,提出了一种基于非常小的三周期表面的多孔聚碳酸酯-聚氨酯半月板植入物。首先,根据膝关节CT扫描结果建立膝关节三维模型[5]。多孔元件由原始最小表面构成。对外半月板结构进行布尔运算后,通过调整表面构造参数,获得一系列不同孔径或孔隙率的植入体结构。然后进行有限元模拟,比较天然半月板和设计多孔半月板在膝关节内关节软骨和双侧半月板的力学变化。结果表明,采用多孔半月板植入物可有效降低股骨软骨和胫骨软骨的压应力和剪切应力集中。同时,多孔种植体结构参数的变化会影响关节软骨的应力。除了具有良好的力学性能外,还可以通过三维打印技术快速形成结构,为临床应用提供了新的思路。
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