Adherence to Treatment and Its Relationship with Anxiety and Depression in Patients with Cardiovascular Disease

Seyed Mojtaba Alavi, S. Montazeri, Zahra Taheri Kharameh
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Abstract

Article type: Original article Background and Aim: Adherence to treatment is of utmost importance for the management of patients with cardiovascular disease. The present study aimed to determine the degree of adherence to treatment and its relationship with anxiety and depression in patients with cardiovascular diseases. Materials and Methods: A cross-sectional study was conducted among patients with cardiovascular disease admitted to teaching hospitals in Qom, Iran in 2016. One hundred sixteen patients who met the inclusion criteria were selected via the convenience sampling method. Data collection instruments included demographic information form, Adherence to Refills and Medications Scale, as well as Hospital Anxiety and Depression Scale. The data were analyzed in SPSS software using descriptive tests and linear regression analysis. Results: Based on the obtained results, about half of the patients (49.1%) scored lower than average in adherence to treatment. The results of multiple linear regression analysis showed that among the variables included in the univariate model (P<0.15), depression (P=-0.26; β = 0.047) and body mass index (BMI) (P=0.22; β = 0.26) were significantly correlated with treatment adherence. Conclusion: As evidenced by the results of the current study, patients' adherence to a medication regimen was associated with depression and BMI. Psychological problems, especially depression, deserve assiduous attention as important determinants of treatment adherence. Article History: Received: 17 January 2021 Revised: 23 February 2021 Accepted: 23 February 2021
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心血管疾病患者治疗依从性及其与焦虑、抑郁的关系
背景与目的:坚持治疗对心血管疾病患者的管理至关重要。本研究旨在确定心血管疾病患者的治疗依从程度及其与焦虑和抑郁的关系。材料与方法:对2016年伊朗库姆教学医院收治的心血管疾病患者进行横断面研究。采用方便抽样法选取符合纳入标准的患者116例。数据收集工具包括人口统计信息表、服药依从性量表和医院焦虑抑郁量表。数据在SPSS软件中进行描述性检验和线性回归分析。结果:根据获得的结果,约有一半(49.1%)患者的治疗依从性评分低于平均水平。多元线性回归分析结果显示,在单变量模型纳入的变量中(P<0.15),抑郁症(P=-0.26;β = 0.047)和身体质量指数(BMI) (P=0.22;β = 0.26)与治疗依从性显著相关。结论:根据目前的研究结果,患者对药物治疗方案的依从性与抑郁和BMI有关。心理问题,特别是抑郁症,作为治疗依从性的重要决定因素,值得认真关注。文章历史:收稿日期:2021年1月17日修改日期:2021年2月23日接收日期:2021年2月23日
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