{"title":"The effect of hypertonic saline on human corneal hydration.","authors":"A J Kempster, J R Larke, J B Marsters","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Hydrophilic gel contact lenses, presoaked in various strength saline solutions, were held in intimate contact with the in vivo human cornea. A change in corneal water content was observed taking place against the induced osmotic gradient. Direct stimulation of some aspect of the mechanisms controlling corneal hydration is postulated, in a manner which may be similar to that previously reported for the in vitro rabbit cornea.</p>","PeriodicalId":76613,"journal":{"name":"The British journal of physiological optics","volume":"30 1","pages":"16-19"},"PeriodicalIF":0.0000,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The British journal of physiological optics","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Hydrophilic gel contact lenses, presoaked in various strength saline solutions, were held in intimate contact with the in vivo human cornea. A change in corneal water content was observed taking place against the induced osmotic gradient. Direct stimulation of some aspect of the mechanisms controlling corneal hydration is postulated, in a manner which may be similar to that previously reported for the in vitro rabbit cornea.