Robotergestützte Lobektomie beim NSCLC: Eine moderne und vielversprechende Methode zur Behandlung – auch von älteren Patienten

K. Hekmat
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Abstract

Introduction: Minimally invasive surgery has become the standard for the early-stage non-small cell lung cancer (NSCLC). The appropriateness of the kind of lung resection for the elderly patients is still debated. Methods: We retrospectively reviewed patients with older than 75 years who underwent robotic lobectomy between May 2016 to June 2022. We selected 103 patients who met the inclusion criteria of the study. The preoperative cardiorespiratory functional evaluations were collected, and the risk of postoperative complications was calculated according to the Charlson Comorbidity Index, the American College of Surgery surgical risk calculator (ACS-NSQIP), EVAD score, and American Society of Anesthesiology (ASA) score. The patients were divided in two groups according to the presence of postoperative complications. Results: Forty-three patients were female, and 72.8% of the total population were former or active smokers. Thirty-five patients reported postoperative complications. The analysis of the two groups showed that the predicted postoperative forced expiratory volumes in the first second (FEV1) and forced vital capacity (FVC) were significantly lower in patients presenting postoperative complications (p = 0.04). Moreover, the upstaging rate and the unexpected nodal metastases were higher in the postoperative complication groups. Conclusion: Robotic-assisted lobectomy for early-stage lung cancer is a safe and feasible approach in selected elderly patients. The factors that could predict the complication rate was the predicted postoperative FEV1 and the nodal disease.
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NSCLC的怀抱手术技术:一种新型、有希望的治疗方法——包括老年病人
微创手术已成为治疗早期非小细胞肺癌(NSCLC)的标准。老年患者的肺切除术的适当性仍然存在争议。方法:我们回顾性分析了2016年5月至2022年6月期间接受机器人肺叶切除术的75岁以上患者。我们选择了103例符合研究纳入标准的患者。收集术前心肺功能评价,根据Charlson合并症指数、美国外科学会手术风险计算器(ACS-NSQIP)、EVAD评分、美国麻醉学会(ASA)评分计算术后并发症风险。根据术后并发症的出现情况将患者分为两组。结果:女性43例,既往吸烟者或活跃吸烟者占总人数的72.8%。35例患者报告术后并发症。两组患者术后并发症预测第一秒用力呼气量(FEV1)和用力肺活量(FVC)均显著降低(p = 0.04)。此外,术后并发症组的抢先期率和意外淋巴结转移率较高。结论:机器人辅助肺叶切除术治疗早期肺癌是一种安全可行的方法。预测术后FEV1和淋巴结病变是预测并发症发生率的因素。
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