Study of left ventricle hypertrophy, dilatation, and ejection fraction changes before and after kidney transplantation

Abstract

Background People with end-stage renal disease (ESRD) are at risk of developing serious cardiovascular complications. Left ventricular hypertrophy is the most prevalent cardiac finding observed. Renal transplantation is the best renal replacement modality offered to these patients with an expected improvement in cardiovascular complications. The aim of this work the present study aims to compare changes in left ventricle hypertrophy, dilatation, and ejection fraction before and after kidney transplantation. Patients and methods This cross-sectional study included 30 renal transplant recipients. Echocardiography was performed for all patients before transplantation and 6–12 months after transplantation. Patients with a reported history of posttransplant rejection or heart failure were excluded from the study. All patients were on hemodialysis before transplantation, and the mean postrenal transplant duration was 10.33 ± 1.95 months. All patients received the same posttransplant immunosuppressive regimen. Results The mean left ventricular ejection fraction before and after renal transplantation was 59.70 ± 7.86 and 68.82 ± 7.93, respectively (P<0.001). The mean left ventricular mass index showed a significant improvement from 144.1 ± 44.15 before transplant to 115.1 ± 38.79 after transplant, with a P value of 0.002. Conclusion According to the results of this study, renal transplantation can improve left ventricle parameters in patients with ESRD.