Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city

S. Anwar, R. Miah, A. Saleh, Humayun Sattar, Sharmeen Ahmed
{"title":"Phenotypic detection of metallo-β-lactamase among the clinical isolates of imipenem resistant Pseudomonas and Acinetobacter in tertiary care hospitals of Dhaka city","authors":"S. Anwar, R. Miah, A. Saleh, Humayun Sattar, Sharmeen Ahmed","doi":"10.3329/IMCJ.V4I2.6498","DOIUrl":null,"url":null,"abstract":"The rapid spread of Metallo-β-lactamase (MBL) producing Gram negative bacilli represents a matter of great concern worldwide. The study analyzed the occurrence of MBL production in carbapenem resistant Pseudomonas and Acinetobacter isolates over one year period. A total of 132 Pseudomonas and 76 Acinetobacter isolates were obtained from two tertiary care hospitals of Dhaka city. A total of 53 Pseudomonas and 29 Acinetobacter isolates were selected because of their resistance to carbapenem specially imipenem (IPM). Screening for MBL production was performed in these isolates by IPM-EDTA microdilution MIC method. 44 (83%) IPM resistant Pseudomonas and 19 (65.5%) Acinetobacter isolates were MBL producer by IPM-EDTA microdilution MIC method. These results suggest that MBL producing Pseudomonas and Acinetobacter isolates are emerging in our country and it is essential to screen carbapenem resistant isolates for MBL production. DOI: 10.3329/imcj.v4i2.6498 Ibrahim Med. Coll. J. 2010; 4(2): 63-65","PeriodicalId":226732,"journal":{"name":"Ibrahim Medical College Journal","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2010-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ibrahim Medical College Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/IMCJ.V4I2.6498","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

Abstract

The rapid spread of Metallo-β-lactamase (MBL) producing Gram negative bacilli represents a matter of great concern worldwide. The study analyzed the occurrence of MBL production in carbapenem resistant Pseudomonas and Acinetobacter isolates over one year period. A total of 132 Pseudomonas and 76 Acinetobacter isolates were obtained from two tertiary care hospitals of Dhaka city. A total of 53 Pseudomonas and 29 Acinetobacter isolates were selected because of their resistance to carbapenem specially imipenem (IPM). Screening for MBL production was performed in these isolates by IPM-EDTA microdilution MIC method. 44 (83%) IPM resistant Pseudomonas and 19 (65.5%) Acinetobacter isolates were MBL producer by IPM-EDTA microdilution MIC method. These results suggest that MBL producing Pseudomonas and Acinetobacter isolates are emerging in our country and it is essential to screen carbapenem resistant isolates for MBL production. DOI: 10.3329/imcj.v4i2.6498 Ibrahim Med. Coll. J. 2010; 4(2): 63-65
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
达喀市三级医院耐亚胺培南假单胞菌和不动杆菌临床分离株金属β-内酰胺酶表型检测
产生金属β-内酰胺酶(MBL)的革兰氏阴性杆菌的迅速传播引起了全世界的高度关注。本研究分析了耐碳青霉烯假单胞菌和不动杆菌在一年内产生MBL的情况。从达卡市的两家三级医院共分离出132株假单胞菌和76株不动杆菌。对碳青霉烯类特别是亚胺培南(IPM)耐药的假单胞菌53株,不动杆菌29株。采用IPM-EDTA微稀释MIC法对这些分离株进行MBL产率筛选。IPM- edta微稀释MIC法产生MBL的假单胞菌44株(83%),不动杆菌19株(65.5%)。这些结果表明,生产MBL的假单胞菌和不动杆菌分离株在我国正在出现,筛选耐碳青霉烯类分离株是生产MBL的必要条件。DOI: 10.3329/imc .v4i2.6498 Ibrahim Med. Coll。j . 2010;4 (2): 63 - 65
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Non-fatal drowning in under-five rural children of Bangladesh Detection of OXA-181/OXA-48 carbapenemase producing Enterobacteriaceae in Bangladesh Use of antibiotics in selected tertiary and primary level health care centers of Bangladesh Effects of aqueous and ethanolic extracts of Aegle marmelos (BAEL) leaves on chronic inflammation in rats Jejunal inflammatory fibroid polyp: a rare cause of intussusception
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1