Synthesis and pharmacological properties of 2,4-disubstituted 5-amino-6-pyrimidinecarboxylic acid derivatives. Part II.
R Jasztold-Howorko, Z Machoń, M Wilimowski, W Wojewódzki, J Barczyńska, L Kedzierska, K Orzechowska-Juzwenko, E Duś, M Rutkowska, A Szelag
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引用次数: 0
Abstract
2,4-Disubstituted 5-amino-6-pyrimidinecarboxylic acid derivatives 5-20 were synthesized and evaluated for their pharmacological activity. Compounds 11-14, 17-19 showed antiaggressive effect, compounds 5, 8, 9, 11, 12 and 19 displayed antiserotonin activity while compound 14 exerted antireserpine action.
2,4-二取代5-氨基-6-嘧啶羧酸衍生物的合成及药理性质。第二部分。
合成了2,4-二取代5-氨基-6-嘧啶羧酸衍生物5-20，并对其药理活性进行了评价。化合物11-14、17-19具有抗侵袭作用，化合物5、8、9、11、12和19具有抗血清素活性，化合物14具有抗利血平作用。
本文章由计算机程序翻译，如有差异，请以英文原文为准。
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