Experience of Endoscopic Ultrasound Fine Needle Aspiration in Tertiary Care Hospital

Abstract

OBJECTIVE: The objective of the study is to determine the spectrum of endoscopic ultrasound fine needle aspiration ( EUS FNA) in the diagnosis of the pancreas, GIT, hepatopancreatobiliary tract, mediastinal lymph node and hepatic lymh node by using rapid on-site evaluation (ROSE). METHODOLOGY: A retrospective study was conducted at the department of Histopathology and endoscopy suit (Liaquat National Hospital and Medical College) during the period of March 2019 to March 2022. A total of 55 patients undergoing EUS FNA were included in our study. 22 gauge needle was used for performing EUS FNA and stained with PAP alcohol fixed slides while stained with Diff –Quick air dried slides, as well as sample, also needed for cell block preparation. RESULTS: The mean age of the patient was 56.1. A total of 55 patients were included among them 33 patients were males and 22 females. The most common site was the pancreas, 38 cases with diagnosed as 68.4% were adenocarcinoma, mediastinal lymh node 9 cases 6.4%, gastric 4 cases 7.3%, rectal 1 case 1.8%, duodenal 1 case 1.8%, hilar mass 1 case 1.8% and hepatic lymh node 1 case 1.8%. CONCLUSION: EUS FNA is a valuable, safe procedure that can be done under conscious sedation but rare complications included bleeding and pancreatitis. It provides at least a cost-effective mode of provisional diagnosis for the diagnosis and cost-effective testing of the pancreas, GIT, post mediastinum or related organs. Close interaction with cytopathologists is essential to improve diagnostic yields. The final diagnosis is based upon the correlation of clinical, EUS and cytological features along with relevant immunohistochemical markers on paraffin embedded block.