Relationship of Clinical Symptoms, Comorbidities and Treatment Options along with Disease Outcomes in Individuals Tested for COVID-19 in Pakistan: A National Survey

N. Butt, Z. Ahmed, M. Khan, Amtullah Zarreen, A. Basit, N. Iqbal, Marium Soomro, S. Abbasi
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Abstract

Background: This web-based survey is done to collect and assess data from people tested for COVID-19 with PCR in Pakistan. Methods: This 3-month study is a cross-sectional online survey, conducted by Pakistan Islamic Medical Association (PIMA), Health Research Advisory Board (HealthRAB) and National Institute of Health (NIH). Data collection was done using Google Forms. People who were tested for COVID-19 using Polymerase Chain Reaction (PCR) were included in the study. The sample size of the study was 1,537. SPSS version 22 was used for data analysis. Results: Majority of the respondents belonged to the age group 20 - 39 years. The most common symptoms found were fever 633 (41%), cough 534 (34%), generalized body aches 432 (28%) and sore throat 392 (25%). The mean COVID-19 mental health score was 3.59 (SD: 5.808, range: 0-18). Treatment with antibiotics and painkillers had a strong correlation (p-value < 0.05) with the disease outcomes. The disease outcomes had moderate correlation (p-value < 0.05) with anti-allergy, steroids, plasma and oxygen therapy, and weak correlation (p-value < 0.05) with Antiviral and Antimalarial therapy. Out of the total respondents, 561 (36.1%) were cured from COVID-19, 14 (0.9%) were expired during/after hospitalization, 15 (1%) were still infected and 962 (62%) were not infected. Conclusion: Pakistani population has a better cure rate than some of its neighboring countries. However, further research in this area is required to draw a definite conclusion.
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巴基斯坦COVID-19检测个体的临床症状、合并症和治疗方案与疾病结局的关系:一项全国性调查
背景:这项基于网络的调查旨在收集和评估巴基斯坦用PCR检测COVID-19的人的数据。方法:这项为期3个月的研究是一项横断面在线调查,由巴基斯坦伊斯兰医学协会(PIMA)、卫生研究咨询委员会(HealthRAB)和国家卫生研究所(NIH)进行。数据收集使用谷歌表单完成。使用聚合酶链反应(PCR)检测COVID-19的人被纳入研究。该研究的样本量为1537人。使用SPSS version 22进行数据分析。结果:大多数受访者年龄在20 - 39岁之间。最常见的症状是发热633例(41%)、咳嗽534例(34%)、全身疼痛432例(28%)和喉咙痛392例(25%)。平均COVID-19心理健康评分为3.59 (SD: 5.808,范围:0-18)。抗生素和止痛药治疗与疾病结局有很强的相关性(p值< 0.05)。疾病结局与抗过敏、类固醇、血浆和氧治疗有中度相关性(p值< 0.05),与抗病毒和抗疟治疗有弱相关性(p值< 0.05)。其中治愈561例(36.1%),住院期间或住院后死亡14例(0.9%),仍感染15例(1%),未感染962例(62%)。结论:巴基斯坦人口的治愈率高于其周边一些国家。然而,这一领域需要进一步的研究才能得出明确的结论。
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