A. Abedi, Serhat Çelik, Zeynep Dilan Özçelik Yılmaz, Z. Güven, H. Akalın, L. Kaynar
{"title":"Donor cell leukemia after allogeneic hematopoietic stem cell transplantation: a case report","authors":"A. Abedi, Serhat Çelik, Zeynep Dilan Özçelik Yılmaz, Z. Güven, H. Akalın, L. Kaynar","doi":"10.51271/jchor-0011","DOIUrl":null,"url":null,"abstract":"A 48-year-old man was diagnosed Acute myeloid leukemia with FLT3 ITD positive and PML/RAR?- negative. Remission was \nachieved after induction and consolidation chemotherapy. Allogeneic hematopoietic stem cell transplantation was performed \nfrom his full matched sibling donor. He relapsed after 5 years and his bone marrow examination revealed PML/RAR?-\npositive Acute promyelocytic leukemia. t(15:17) was positive and FLT-3 ITD was negative. Cytogenetic and molecular analysis \nconfirmed donor cell origin. Donor didn’t develop Acute promyelocytic leukemia.","PeriodicalId":171029,"journal":{"name":"Journal of Current Hematology & Oncology Research","volume":"34 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Current Hematology & Oncology Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.51271/jchor-0011","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A 48-year-old man was diagnosed Acute myeloid leukemia with FLT3 ITD positive and PML/RAR?- negative. Remission was
achieved after induction and consolidation chemotherapy. Allogeneic hematopoietic stem cell transplantation was performed
from his full matched sibling donor. He relapsed after 5 years and his bone marrow examination revealed PML/RAR?-
positive Acute promyelocytic leukemia. t(15:17) was positive and FLT-3 ITD was negative. Cytogenetic and molecular analysis
confirmed donor cell origin. Donor didn’t develop Acute promyelocytic leukemia.
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