Behavior of biomaterials in relation to the conservation time and temperature: stability test of a bioproduct

Joab de Souza Arouche
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Abstract

All products before reaching the consumer's table go through a battery of analyzes, in order to check if these materials resist the weather, temperature, climate changes, friction, including transportation. Whether they really support physical, chemical and biological factors and also with the idea of estimating the useful life of these materials. Biomaterials are no different, all bioproducts are also subjected to resistance tests to reach industry, or long-term production. Among the numerous possibilities that exist for the application of biomaterials, recently the bioactive ones encapsulated in polymeric nanoparticles of controlled action stand out with their several alternatives of application, among them as natural insecticides, aiming at the reduction of conventional pesticides, including fungicides, used in the activation and controlled release of the drug.Thus, this research aims to develop a formulation and verify its behavior as a function of time and temperature (25 °C), as well as the application of different preservatives. , [phenoxyethanol-2-methyl-2H-isothiazolin-3-one-NE), citric acid and thymol] in order to verify its influence on the stability of the formulations as a function of time. Among all tested formulations, the one containing the preservative NE was the only one approved in all parameters.
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生物材料与保存时间和温度的关系:生物制品的稳定性试验
所有产品在到达消费者的桌子之前都要经过电池分析,以检查这些材料是否能抵抗天气、温度、气候变化、摩擦,包括运输。它们是否真的支持物理,化学和生物因素以及估计这些材料的使用寿命的想法。生物材料也不例外,所有生物制品也都要经过抗性测试才能进入工业生产,或长期生产。在生物材料应用的众多可能性中,最近被包裹在具有控制作用的聚合纳米颗粒中的生物活性材料因其几种替代应用而脱颖而出,其中包括作为天然杀虫剂,旨在减少用于药物激活和控制释放的传统杀虫剂,包括杀菌剂。因此,本研究旨在开发一种配方并验证其作为时间和温度(25°C)的函数的行为,以及不同防腐剂的应用。,[苯氧乙醇-2-甲基- 2h -异噻唑啉-3- 1 - ne],柠檬酸和百里香酚],以验证其对配方稳定性的影响作为时间的函数。在所有测试的配方中,含有防腐剂NE的配方是唯一一个在所有参数中都被批准的配方。
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