Pharmacological and psychotherapy pain management in adult acute lymphoblastic leukemia (ALL) with depressive organic disorder patient

Regina Astari Tjoegito, I. Wardani
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Abstract

Background: Acute Lymphoblastic Leukemia (ALL) or also called Acute Lymphocytic Leukemia is a cancer of the blood and bone marrow. ALL is strongly related to pain due to the nature of the disease where leucocyte cells infiltrate organs causing pain, and also due to some of its treatments which can cause pain as a side effect. Case report: A female patient, aged 45 years, consulted the Consultation-Liaison Psychiatry, sub-Palliative Department with a complaint of pain. The patient felt severe pain, intermittent but kept getting worse over time, with VAS of 7-8 causing her to feel weak and have difficulty sleeping, with a history of Paracetamol and Codeine as analgetic. When the pain peaked, the patient felt weak and sometimes crying for no reason. She became more emotional since her illness and she’s not an emotional person before. Patients also tend to get tired and lost enthusiasm in doing activities. Patient with anankastic personality character, acting out, and sublimation defense mechanism, was diagnosed with Organic Depressive Disorder (F06.32); ALL ECOG2, mild anemia, suspect CAD with differential diagnosis of ischemic due to supply & demand mismatch (anteroseptal ischemia), uterine mass et causa suspected leukemic infiltration with differential diagnosis of uterine myoma.
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成人急性淋巴细胞白血病(ALL)合并抑郁性器质性障碍患者的药物和心理治疗疼痛
背景:急性淋巴母细胞白血病(Acute Lymphoblastic Leukemia, ALL)又称急性淋巴细胞白血病(Acute Lymphocytic Leukemia),是一种血液和骨髓的癌症。ALL与疼痛密切相关,因为这种疾病的性质是白细胞浸润器官引起疼痛,也因为它的一些治疗方法可能导致疼痛作为副作用。病例报告:一名女性患者,年龄45岁,以疼痛主诉就诊于亚姑息科会诊联络精神病学。患者感到剧烈疼痛,间歇性疼痛,但随着时间的推移不断加重,VAS评分为7-8,导致她感到虚弱,难以入睡,并有扑热息痛和可待因的止痛史。当疼痛达到顶峰时,病人感到虚弱,有时会无缘无故地哭泣。自从生病后,她变得更情绪化了,而她以前不是一个情绪化的人。患者也容易感到疲倦,失去活动的热情。患者具有躁动型人格特征、行为表现和升华防御机制,诊断为器质性抑郁症(F06.32);ALL ECOG2,轻度贫血,疑似CAD伴供需不匹配缺血性鉴别诊断(房间隔缺血),子宫肿块等引起疑似白血病浸润伴子宫肌瘤鉴别诊断。
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