Growing weapons to fight hemophilia

P. Mannucci
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Abstract

Very few rare diseases have witnessed the gigantic progress in patient care that took place for the hemophilias in the last 20 years. The first landmark was in the 1990s, when recombinant DNA technology afforded the industrial production, regulatory approval and commercialization of an array of factor VIII (FVIII) and factor IX (FIX) products, potentially available in unlimited quantity, efficacious and free from the risk of transmission of such bloodborne infections as HIV and the hepatitis virus B and C [...].
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研发对抗血友病的武器
在过去的20年里,很少有罕见疾病见证了血友病患者护理的巨大进步。第一个里程碑是在20世纪90年代,当时重组DNA技术提供了一系列因子VIII (FVIII)和因子IX (FIX)产品的工业生产、监管批准和商业化,这些产品可能无限量供应,有效且没有传播艾滋病毒、乙型肝炎病毒和丙型肝炎病毒等血源性感染的风险[…]。
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