{"title":"Algorithms for Calculation of Parameters of Electrochemical Biosensor","authors":"V. Shumyantseva, V. Pronina","doi":"10.18097/bmcrm00178","DOIUrl":null,"url":null,"abstract":"The aim of this work is to present the experimental results in the form of an algorithm for analyzing the modification of screen printed electrodes, including the possibility of its regeneration for irreversibly oxidizing biologically active compounds (drugs, DNA and proteins). A protocol was developed for quantitative analysis and study of the mechanism of drug-DNA interaction by differential pulse voltammetry, including the following parameters: complex binding constant, Gibbs free energy, and electrochemical coefficients of the toxic effect.","PeriodicalId":286037,"journal":{"name":"Biomedical Chemistry: Research and Methods","volume":"25 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biomedical Chemistry: Research and Methods","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18097/bmcrm00178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The aim of this work is to present the experimental results in the form of an algorithm for analyzing the modification of screen printed electrodes, including the possibility of its regeneration for irreversibly oxidizing biologically active compounds (drugs, DNA and proteins). A protocol was developed for quantitative analysis and study of the mechanism of drug-DNA interaction by differential pulse voltammetry, including the following parameters: complex binding constant, Gibbs free energy, and electrochemical coefficients of the toxic effect.
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