[The involvement of intracellular regulatory systems in the mechanisms of the recovery of the neuronal activity of the cerebral cortex in anoxia].

M O Samoĭlov, D G Semenov, E I Tiul'kova, E A Bolekhan
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Abstract

Changes in the membrane-bound calcium (Ca(b)), polyphosphoinositides (PPI) and cAMP, as well as unit spike activity of the cat brain cortex were studied during 30 min of recovery after 5-min anoxia. The cats with poor recovery revealed low Ca(b) and PPI but high level of the cAMP content. The group of cats with more successful restitution after anoxia revealed a sharp increase in the Ca(b) and PPI and not in the cAMP.

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[细胞内调节系统在缺氧情况下大脑皮层神经元活动恢复机制中的作用]。
在缺氧5分钟后恢复30分钟,研究猫脑皮层膜结合钙(Ca(b))、多磷酸肌苷(PPI)和cAMP的变化以及单位峰值活性。恢复较差的猫Ca(b)和PPI较低,cAMP含量较高。缺氧后恢复更成功的猫组显示Ca(b)和PPI急剧增加,而cAMP没有增加。
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