{"title":"Berberine, a potential drug for trachoma.","authors":"P K Khosla,&nbsp;V I Neeraj,&nbsp;S K Gupta,&nbsp;G Satpathy","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The clinical serological response to topical treatment of trachoma with Berberine an indigenous drug has been studied in 32 microbiologically confirmed cases. Efficacy of Berberine 0.2% when compared to sulfacetamide 20% was found to be superior in both the clinical course of trachoma and in achieving a fall in the serum antibody titers (P < 0.05) against chlamydia trachomatis in the treated patients.</p>","PeriodicalId":77361,"journal":{"name":"Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation...","volume":"69 ","pages":"147-65"},"PeriodicalIF":0.0000,"publicationDate":"1992-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue internationale du trachome et de pathologie oculaire tropicale et subtropicale et de sante publique : organe de la Ligue contre le trachome avec la collaboration de l'International Organization against Trachoma et des organisation...","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

The clinical serological response to topical treatment of trachoma with Berberine an indigenous drug has been studied in 32 microbiologically confirmed cases. Efficacy of Berberine 0.2% when compared to sulfacetamide 20% was found to be superior in both the clinical course of trachoma and in achieving a fall in the serum antibody titers (P < 0.05) against chlamydia trachomatis in the treated patients.

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小檗碱,一种治疗沙眼的药物。
临床血清学反应局部治疗沙眼用小檗碱一种本土药物已经研究了32例微生物确诊病例。在沙眼的临床病程和治疗患者沙眼衣原体血清抗体滴度的下降(P < 0.05)方面,0.2%的小檗碱的疗效优于20%的磺胺乙酰胺。
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[Ocular manifestations of vitamin A deficiency and their prevention]. [Information and education interventions on hygiene levels of a population in which trachoma exists in a hyperendemic and serious form]. [Cause of blindness in the province of Giang-Vietnam]. [Identification of latent forms of Chlamydia trachomatis in the conjunctiva signifying "new interpretation of ocular chlamydia infections"]. [Curriculum at the Institute of Tropical Ophthalmology of Africa at Bamako (IOTA)].
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