Akzelerierte Atherosklerose - Chronische Niereninsuffizienz ist ein etablierter kardiovaskulärer Risikofaktor

Abstract

accelerated atherosclerosis in renal insufficency. Nevertheless, there are several uremia-related risk factors such as proteinuria, anemia, or disorders in calcium-phosphate metabolism (hyperparathyroidism) contributing to an increased cardiovascular mortality. In patients with impaired renal function there is a high incidence of asymptomatic coronary artery disease. Coronary angiography should be performed as frequent as done in patients with normal kidney function. To the treatment strategy of coronary artery disease in patients with impaired kidney function account medical therapy, percutaneous transluminal coronary angioplasty (PTCA/stent) or revascularization with coronary artery bypass surgery (CABG). For both interventional procedures the degree of impairment of kidney function is significantly associated with increased morbidity and mortality. To improve the poor prognosis of patients with any degree of renal insufficiency and coronary artery disease everything should be done to preserve kidney function at first and secondly to treat them as good as patients with normal kidney function and coronary artery disease.