The Diagnostic Model of Obstructive Sleep Apnea Hypopnea Syndrome Based on Artificial Neural Networks

Bin Jing, Hai-Bin Meng, Songchun Yang, Xue-Yi Shang, Dong-Sheng Zhao
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引用次数: 2

Abstract

Obstructive sleep apnea hypopnea syndrome (OSAHS) is a kind of breathing regulator disorder disease in sleep, which is related to many complex factors and not yet fully elucidated the pathological state. This pathological state is not only related to snoring, excessive daytime sleepiness (EDS), also due to hypopnea or apnea caused by repeated episodes of hypoxia and hypercapnia, which can lead to the complications of cardiopulmonary and other vital organs even to sudden death. So OSAHS is a potential fatal disease, which has been widely appreciated in clinic. The target of dealing with OSAHS was not only to decrease the mortality rate, but also to minimize the potential adverse effects. Therefore, it was important to detecting, preparation and treatment early in clinic, especially how to detect as soon as possible. In this study, the diseases diagnosis was realized by using multilayer, probabilistic, logic model, and generalized regression neural networks. The diseases dataset was prepared by patients' case reports from No.307 hospital of PLA's database and volunteers' experiments. By which, built a model to analysis a number of parameters associated to OSAHS.
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基于人工神经网络的阻塞性睡眠呼吸暂停低通气综合征诊断模型
阻塞性睡眠呼吸暂停低通气综合征(OSAHS)是一种睡眠呼吸调节障碍性疾病,与许多复杂因素有关,其病理状态尚未完全阐明。这种病理状态不仅与打鼾、日间过度嗜睡(EDS)有关,还与反复发作的缺氧、高碳酸血症引起的低呼吸或呼吸暂停有关,可导致心肺等重要器官的并发症,甚至猝死。因此,OSAHS是一种潜在的致死性疾病,已被临床广泛认识。治疗OSAHS的目标不仅是降低死亡率,而且要尽量减少潜在的不良反应。因此,在临床早期发现、早期准备和早期治疗,特别是如何尽早发现具有重要意义。本研究采用多层、概率、逻辑模型和广义回归神经网络实现疾病诊断。疾病数据集由解放军第307医院数据库的患者病例报告和志愿者实验组成。在此基础上,建立了一个模型,对OSAHS相关的多个参数进行了分析。
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