A Case Report of Gardner-Associated Fibroma in 19-Month-Old Girl

Ho Lee, Ji-Won Han, J. Youn, Hyun Young Kim
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Abstract

Gardner-associated fibroma (GAF) is a benign lesion of soft tissue which has recently been described and is exceedingly rare in children. GAF is associated with adenomatous polyposis coli gene mutation, familial adenomatous polyposis and desmoid. We report a case of patient with soft tissue tumor on her lower back which was turned out to be GAF. The patient was a 19-month-old female who visited out-patient clinic with palpable mass on her lower back and we performed surgical excision. The tumor was located at subcutaneous and we excised the tumor including surrounding soft tissue. She discharged without any complication on surgery day. The pathologic report showed dense collagenous tissue with spindle cell and adipose tissue, suggestive of GAF. We are planning to check gene study and to perform endoscopy and abdominal ultrasonography for at the age of 4.
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19月龄女童加德纳相关纤维瘤1例报告
加德纳相关纤维瘤(GAF)是一种最近被描述的软组织良性病变,在儿童中极为罕见。GAF与大肠腺瘤性息肉病基因突变、家族性腺瘤性息肉病和硬纤维瘤有关。我们报告一个病人的软组织肿瘤在她的下背部,原来是GAF。患者是一名19个月大的女性,她因下背部可触及肿块而去门诊就诊,我们进行了手术切除。肿瘤位于皮下,我们切除了肿瘤及周围软组织。手术当天出院,无任何并发症。病理报告显示胶原组织致密,有梭形细胞和脂肪组织,提示GAF。我们计划在4岁时进行基因检查,并进行内窥镜检查和腹部超声检查。
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