Hypertrophic obstructive cardiomyopathy diagnosed during regadenoson stress test

Abstract

Regadenoson (REG) is a selective adenosine A2a receptor agonist which is used as an agent to induce vasodilation for the nuclear myocardial perfusion stress test in patients with suspected coronary artery disease (1). Here we report a case where REG infusion caused immediate accentuation of a murmur with an increase in the left ventricular outflow tract (LVOT) gradient, which led to the diagnosis of hypertrophic obstructive cardiomyopathy (HOCM) in this patient.