Post injection transmission scanning in a volume imaging PET camera

1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference Pub Date : 1993-10-31 DOI:10.1109/NSSMIC.1993.373525

R. Smith, J. Karp

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引用次数: 27

Abstract

Quantitative, low noise, measured attenuation correction has been established for the PENN PET 240H Volume Imaging Camera. This is achieved, without septa, using a narrow energy (450-570 keV) and sinogram position (2 cm wide mask) gate to minimize scatter contamination. Twelve minute transmission acquisitions with a 0.5 mCi rod source are adequate for this purpose. Post injection transmission scans (with emission activity in the FOV) suffer from emission contamination simulating transmitted gamma ray flux. This emission contamination may be measured by performing a transmission acquisition without a transmission source. This contamination is then subtracted from the measured post injection transmission scan. Emission activity within the FOV adds to detector deadtime so that more counts are lost than are added by the emission activity counts accepted into the transmission position gate. Thus there is a net loss of scan statistics when compared to pre-injection transmission scanning. Removal of emission contamination and compensation for this excess deadtime results in corrected attenuation coefficients. For residual activity levels typical of FDG whole-body cancer and cardiac studies the post injection measurements are within 4% of pre-injection values. This method is under refinement to correct for attenuation with higher levels of activity in the FOV.<>

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体成像PET相机注射后透射扫描

建立了PENN PET 240H体像相机的定量、低噪声、实测衰减校正方法。这是实现的，没有隔膜，使用窄能量(450- 570kev)和sinogram位置(2厘米宽掩膜)栅极，以尽量减少散射污染。12分钟传输采集与0.5 mCi棒源是足够的，用于此目的。注射后透射扫描(视场内具有发射活动)受到模拟透射伽马射线通量的发射污染的影响。这种排放污染可以通过在没有传输源的情况下进行传输采集来测量。然后从测量的注射后传输扫描中减去这种污染。视场内的发射活动增加了探测器的死区时间，因此丢失的计数比接收到传输位置门的发射活动计数所增加的计数要多。因此，与注射前传输扫描相比，存在扫描统计数据的净损失。去除排放污染并补偿这一过量死区时间可得到校正的衰减系数。对于典型的FDG全身癌症和心脏研究的残留活性水平，注射后测量值在注射前值的4%以内。该方法正在改进中，以纠正视场中较高活动水平的衰减。

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1993 IEEE Conference Record Nuclear Science Symposium and Medical Imaging Conference

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