The association of bacterial infection with intracranial aneurysm disease

Mikko J. Pyysalo, T. Pessi, Joona Hallikainen, J. Frösen
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Abstract

The human body abounds in micro-organisms that maintain the vital balance of the internal ecosystem. Though it is well known that several benefit the human body while others are linked to disease, how the microbiota affects the pathology of intra-cranial aneurysms is an interesting arena that still requires exploration. Studies have suggested possible association between the excess of bacteria, such as those causing gingivitis, as well the deficit of bacteria, such as loss of gut flora due to antibiotics, to intracranial aneurysms and their subsequent behavior. The authors review existing literature on the subject and outline the scope for further research on the subject.
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细菌感染与颅内动脉瘤疾病的关系
人体内有大量的微生物,它们维持着体内生态系统的重要平衡。虽然众所周知,有几种对人体有益,而另一些则与疾病有关,但微生物群如何影响颅内动脉瘤的病理是一个有趣的领域,仍需要探索。研究表明,细菌过量(如引起牙龈炎的细菌)和细菌不足(如抗生素导致的肠道菌群损失)与颅内动脉瘤及其后续行为之间可能存在关联。作者回顾了有关该主题的现有文献,并概述了该主题进一步研究的范围。
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