An augmented regenerative technique for severe osseous defects.

V J Iacono, K Demerel, S M Zove, S Holen, P N Baer
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Abstract

Techniques for new attachment using the principle of guided tissue regeneration with barrier membranes have become accepted as a method for treating teeth with severe osseous defects and furcation involvement. After an evaluation of existing membranes and techniques, a procedure was developed using an expanded polytetrafluoroethylene soft tissue patch, 1 mm thick (W. L. Gore and Assoc., Flagstaff, AZ), in conjunction with an alloplast hydroxylapatite bone substitute (HA-500, 40-60 mesh) (Orthomatrix, Minneapolis, MN), to maintain a space for the maturation of the blood clot. An in vitro study of microbial adherence to the soft tissue patch indicated that the number of attached Streptococcus sanguis (gordonii) G9B, and Actinomyces viscosus T14 (V) cells was significantly lower (P < .005 and P < .025, respectively) than the number of bacteria that attached to Gore-Tex Periodontal Material. Two case reports are presented to demonstrate the successful use of the soft tissue patch augmented with hydroxylapatite in patients exhibiting furcation involvement and severe vertical osseous defects.

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一种用于严重骨缺损的增强再生技术。
使用屏障膜引导组织再生原理的新附着体技术已成为治疗严重骨缺损和分叉受损伤牙齿的一种方法。在对现有膜和技术进行评估后,开发了一种使用1毫米厚的膨胀聚四氟乙烯软组织贴片的程序(W. L. Gore和协会)。与羟基磷灰石同种异体骨替代物(HA-500, 40-60目)(orthommatrix, Minneapolis, MN)联合使用,为血凝块的成熟维持空间。体外微生物对软组织贴片的粘附研究表明,血链球菌(Streptococcus sanguis (gordonii) G9B)和粘放线菌T14 (V)细胞的粘附数量显著低于Gore-Tex牙周材料的粘附数量(P < 0.005和P < 0.025)。两个案例报告提出,以证明成功使用的软组织贴片增强羟基磷灰石在患者表现出分叉受损伤和严重的垂直骨缺损。
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