STUDY OF BACTERIURIA AMONG PREGNANT WOMEN ATTENDING A TERTIARY CARE HOSPITAL IN PANIPAT DISTRICT, INDIA

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Abstract

Most common population at risk for both symptomatic urinary tract infection (UTI) and asymptomatic bacteriuria, however, is sexually active women. Although asymptomatic infection in this group does not clearly produce serious medical problems, it may be a predictor of future symptomatic infection. Women are more susceptible to infection than men because of the shorter length of the female urethra. Perineal bacterial microbiota that originate in the gastrointestinal tract are the usual pathogens, especially if the bacteria possess factors that facilitate their binding to the uroepithelium. Sexual intercourse facilitates entry of the bacteria into the female urethra. Pregnant women are extra at risk of expand UTIs due to physiological adjustments withinside the urinary tract. UTI constitute severe threats to human health worldwide and hundreds of thousands of the humans affected every year. The aim of this study was to know the prevalence and antimicrobial susceptibility pattern of isolates in pregnant female patients. A total two hundred pregnant and non-pregnant females patients had been included on this study after obtaining the consent. Under strict aseptic precautions midstream urine samples had been taken from all sufferers. All the samples had been processed with the aid of using the usage of standard bacteriological methods i.e. wet mount, inoculation on blood agar and MacConkey's agar after which diagnosed with the aid of using standard biochemical tests, antibiotic sensitivity trying out changed into completed with the aid of using Kirby Bauer's disc diffusion method. In this study 80 out of 200 females patient i.e. 40% were showed UTI of which a most of 20 to 30 years age group had a considerably better occurrence of UTI i.e. 56.25%, while the age group of 60 years and above suggests the lowest contamination rate i.e 2.5% as compared to others. Females belonging to lower socioeconomic status had been extra liable to UTI then others. Pregnant females were more prone to UTI then non-pregnant females i.e. 52.73% and 35.17% respectively. Amongst pregnant females, primigravida and those in the first and second trimesters had been at higher risk. All isolates had been sensitivity to ampicillin+sulbactam, sparfloxacin, and gatifloxacin. Our study mentioned that the prevalence of UTIs was 40%; the pregnant female patients were more prone to UTI than non-pregnant females. The most isolated microorganism had been Escherichia coli which was maximum accountable for UTIs. The sexually active age group 26-30 years was highly at risk of UTI. Females belonging to lower socioeconomic status had been extra liable to contamination. Pregnancy was one in each of the predisposing elements for UTI. All isolates had been confirmed sensitivity to ampicillin+sulbactam, sparfloxacin, and gatifloxacin.
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印度帕尼帕特地区一家三级保健医院孕妇的细菌研究
然而,最常见的有症状性尿路感染(UTI)和无症状性细菌尿风险的人群是性活跃的女性。虽然该组无症状感染不会明显产生严重的医疗问题,但它可能是未来有症状感染的预测因素。由于女性尿道较短,女性比男性更容易受到感染。起源于胃肠道的会阴细菌微生物群是常见的病原体,特别是如果这些细菌具有促进它们与尿上皮结合的因子。性交有助于细菌进入女性尿道。由于尿路内的生理调整,孕妇更容易发生扩张性尿路感染。尿路感染对全世界人类健康构成严重威胁,每年有数十万人受到影响。本研究的目的是了解妊娠女性患者中分离株的流行情况和药敏模式。在获得同意后,共有200名怀孕和非怀孕的女性患者被纳入本研究。在严格的无菌预防措施下,从所有患者身上提取了中游尿液样本。所有样品均采用标准的细菌学方法湿贴、血琼脂接种和麦康基琼脂处理,诊断后采用标准的生化试验,抗生素敏感性试验改为采用Kirby Bauer圆盘扩散法完成。在本研究中,200例女性患者中有80例(40%)出现UTI,其中20 ~ 30岁年龄组的UTI发生率较高,为56.25%,60岁及以上年龄组的污染率最低,为2.5%。社会经济地位较低的女性更易发生尿路感染。孕妇感染尿路感染的发生率高于非孕妇,分别为52.73%和35.17%。在怀孕的女性中,初产妇和孕早期和孕中期的女性风险更高。所有分离株均对氨苄西林+舒巴坦、斯帕沙星和加替沙星敏感。我们的研究提到尿路感染的患病率为40%;妊娠女性患者较未妊娠女性更易发生尿路感染。分离到最多的微生物是大肠杆菌,它是造成uti的主要原因。26-30岁的性活跃年龄组是尿路感染的高危人群。社会经济地位较低的女性更容易受到污染。妊娠是尿路感染的诱因之一。所有分离株均证实对氨苄西林+舒巴坦、斯帕沙星和加替沙星敏感。
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