A Case of Sarcoidosis Associated with Recurrent Many Urinary Tract Calculi Caused by Hypercalcemia

Abstract

We report a 76-year-old man who was diagnosed with bilateral hilar lymphadenopathy and elevated level of angiotensin-converting enzyme 3 years ago, and uveitis 2 years ago. He was performed lithotripsy for bilateral urinary tract calculi 1 year ago and referred to our department for chronic kidney disease. After then, urinary tract calculi relapsed and lithotripsy was performed 5 times and the level of adjusted calcium maintained from 10 to 12 mg/dL. In 2014, the level of creatinine (Cr) increased gradually, and abdominal computed tomography showed as many as 19 urinary tract calculi. We diagnosed this case as sarcoidosis clinically. The frequent recurrence of urinary tract calculi seemed to be caused by hypercalcemia derived from sarcoidosis, so we treated hypercalcemia by prednisolone 30 mg/day. Then the level of calcium and Cr improved rapidly. We should take the probability of sarcoidosis into consideration for the frequent recurrence of urinary tract calculi and hypercalcemia.