Investigation of Anti-inflammatory and Immunomodulatory Effects of Methanolic Extracts of Fenugreek Leaves and Seeds to Justify its Use in Topical Creams for Preventing Inflammation and Joint-Pain

Abstract

Many plants that we consume on a daily basis are known for their medicinal values since ancient times. Research has now once again picked up, to restore those beliefs on a more scientific basis by rigorous investigation and checking of phytochemicals present in the plants. One such plant of interest is Fenugreek (Trigonella foenum-graecum L.). This study includes preparation of crude extracts of Fenugreek leaves and seeds by Soxhlet, phytochemical detection and preliminary screening of Fenugreek secondary metabolites, such as, Flavonoids, Alkaloids, Phenolics, Steroids, Terpenoids, Saponins, etc., followed by depiction of its anti-inflammatory and antioxidant properties and its eventual use in formulating a medicinal cream. Keywords : Anti- inflammatory, Biochemical assays, Fenugreek, Medicinal Plant, Methanolic Extraction, Phytochemical Analysis.