DEGENERATIVE LUMBAR SPONDYLOLISTHESIS: TREATMENT STRATEGIES

R. Stovall, A. Halliday
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Abstract

Degenerative lumbar spondylolisthesis is a heterogenous entity requiring a number of different treatment strategies. Only 10–15% of patients with a symptomatic degenerative spondylolisthesis will require surgical intervention. The traditional surgical treatment has been decompression of the associated stenosis with a laminectomy and medial facetectomies. However, several studies have shown improved outcome with the addition of an intertransverse fusion. Although outcome is improved with fusion, a significant improvement in patient outcome has not been demonstrated with instrumented fusions. Thus, instrumented fusion should be reserved for patients at high risk for a progressive deformity such as patients with excessive motion on preoperative radiographs, a documented progressive slip, and those requiring a discectomy or total facetectomy to adequately decompress the neural elements. The standard type of fusion has been a posterolateral intertransverse fusion with autologous bone. An inter-body fusion may be advantageous when there is severe disc space collapse with narrowing of the neuroforamen, when a discectomy is performed as part of the decompression, or to correct a kyphosis at that motion segment. Randomized, controlled outcome studies evaluating the use of instrumented fusions in subsets of patients with degenerative spondylolisthesis are needed.
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退行性腰椎滑脱:治疗策略
退行性腰椎滑脱是一种异质性实体,需要许多不同的治疗策略。只有10-15%的症状性退行性椎体滑脱患者需要手术干预。传统的手术治疗方法是椎板切除术和内侧面切除术对相关狭窄进行减压。然而,一些研究表明,加入横间融合后,结果有所改善。虽然融合改善了预后,但未证实内固定融合对患者预后有显著改善。因此,对于进行性畸形的高风险患者,如术前x线片上运动过度、有进行性滑动记录的患者,以及需要椎间盘切除术或全面切除术以充分减压的患者,应保留内固定融合。标准的融合类型是与自体骨的后外侧横间融合。当存在严重的椎间盘间隙塌陷伴神经孔狭窄、椎间盘切除术作为减压的一部分或矫正该运动节段的后凸时,椎间融合可能是有利的。需要随机、对照结果的研究来评估在退行性椎体滑脱患者亚群中使用内固定融合的效果。
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