[Infectious spondylodiscitis. Analysis of a series of 105 cases].

D Bontoux, L Codello, F Debiais, G Lambert de Cursay, I Azais, M Alcalay
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Abstract

Among 105 cases of infectious spondylitis diagnosed and treated from 1971 through 1990, 23 were due to tuberculosis (TS) and 82 to other causes (NTS). The annual number of cases of NTS rose over the study period, partly because of an increase in iatrogenic spondylitis, whereas the number of TS cases fell. In both groups, mean age of patients was higher than in earlier studies. The leading causative agents in NTS were staphylococci, followed by streptococci, then Escherichia coli. Diagnosis of spondylitis was dependent on the imaging techniques used; among available methods, the most reliable was magnetic resonance imaging which improved diagnostic performance by detecting early, specific changes. Except in patients with positive blood cultures and in TS patients with Koch bacilli recovered from other visceral foci, bacteriologic diagnosis rested on studies of samples taken from the spinal infection site. Half the subjects underwent discovertebral needle biopsy, with a success rate of 47.5%, a figure comparable with those reported in other studies. In 30% of patients, bacteriologic documentation of the infection was not obtained and diagnosis rested on a set of clinical, biological, and radiological criteria.

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(传染性spondylodiscitis。105例系列病例分析[j]。
在1971年至1990年诊断和治疗的105例传染性脊柱炎中,23例是由于结核病(TS), 82例是由于其他原因(NTS)。在研究期间,每年NTS病例数上升,部分原因是医源性脊柱炎的增加,而TS病例数下降。两组患者的平均年龄均高于早期研究。NTS的主要病原体是葡萄球菌,其次是链球菌,然后是大肠杆菌。脊柱炎的诊断依赖于所使用的成像技术;在现有的方法中,最可靠的是磁共振成像,它通过检测早期的特异性变化提高了诊断性能。除了血培养阳性患者和从其他内脏病灶中恢复了科赫杆菌的TS患者外,细菌学诊断依赖于从脊髓感染部位采集的样本的研究。一半的受试者接受了脊椎穿刺活检,成功率为47.5%,与其他研究报告的数据相当。在30%的患者中,没有获得感染的细菌学记录,诊断依赖于一套临床、生物学和放射学标准。
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