Aiding the Recovery of ICU Survivors: Creation and Implementation of a Post-ICU Recovery Clinic

M. Biehl, K. Sarin, E. Bishop, J. Veith, M. Holztrager, K. Bash, J. O’Brien, H. Khouli
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Abstract

Introduction: Advancements in critical care medicine have led to increase in Intensive Care Unit (ICU) survival. ICU survivors often experience cognitive, mental and physical impairments as part of a condition called Post- Intensive Care Syndrome (PICS). While there are several ICU follow-up programs, there is variability in their structure and approach. We describe the creation and implementation of a Post-ICU Recovery Clinic (PIRC). Methods: A retrospective observational study was conducted and included all patients seen in a PIRC of a quaternary health system from December 2019 to September 2020. PIRC visit variables included scores on several validated questionnaires screening for mental health and cognitive disorders, 6-minute walk test, pulmonary function test, change in occupational and driving status, and referrals made during PIRC visit. Statistics reported reflect exclusion of the missing data points. Results: The criteria utilized for patient selection was circulatory shock, acute respiratory distress syndrome (ARDS), mechanical ventilation >7 days, ICU admission >7 days, delirium, cardiac arrest and COVID-19 with ICU stay >2 days. A total of 63 patients were seen in PIRC, 41% of those were ARDS survivors. Given the COVID-19 pandemic, telemedicine was shortly implemented and 62% of the visits were virtual. Median age (IQR) was 59.1 (49.2-71.6), 59% were male, with near equal Caucasian and African American distribution. All patients who had an in-person visit were seen by a critical care physician and advance practice provider, pharmacist, psychiatrist and physical therapist during the visit. 36% screened positive for anxiety or depression as identified by the Patient Health Questionnaire-4 (PHQ- 4), and 11% screened positive for post-traumatic stress disorder (PTSD) identified by the Primary Care PTSD Screen for DSM-5 (PC-PTSD-5). Of the patients seen with in-person visit, 45% had either mild or moderate cognitive impairment identified by the Montreal Cognitive Assessment (MOCA). Median 6-minute walk distance was 66% predicted. Median FEV1, FVC, and DLCO was 86, 80, and 60% predicted respectively. From the 61% of patients who were working and 91% who were driving prior to hospitalization, only 22% and 65% had returned to those activities respectively. Thirty four (56%) patients had at least one referral made, with some patients receiving up to 6 referrals. Conclusion: A high prevalence of PICS and social impairments were identified in ICU survivors at a PIRC. Incorporating an inter-disciplinary team approach and standardized surveys were imperative to recognize these impairments in order to support return to the best state of recovery possible.
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帮助ICU幸存者康复:ICU后康复诊所的创建和实施
重症监护医学的进步导致重症监护病房(ICU)存活率的增加。ICU幸存者经常经历认知、精神和身体损伤,这是重症监护后综合征(PICS)的一部分。虽然有几个ICU随访项目,但其结构和方法存在差异。我们描述了icu后康复诊所(PIRC)的创建和实现。方法:进行了一项回顾性观察性研究,纳入了2019年12月至2020年9月在某第四卫生系统PIRC就诊的所有患者。PIRC访问变量包括心理健康和认知障碍筛查、6分钟步行测试、肺功能测试、职业和驾驶状态变化以及PIRC访问期间的转诊得分。报告的统计数据排除了缺失的数据点。结果:患者选择标准为循环性休克、急性呼吸窘迫综合征(ARDS)、机械通气7 d、入院ICU 7 d、谵妄、心脏骤停、COVID-19合并ICU住院2 d。PIRC共观察到63例患者,其中41%为ARDS幸存者。鉴于2019冠状病毒病大流行,远程医疗很快就得到了实施,62%的就诊是虚拟的。中位年龄(IQR)为59.1(49.2-71.6),59%为男性,白种人和非裔美国人分布接近相等。所有患者在就诊期间均由重症监护医师、高级执业医师、药剂师、精神科医生和物理治疗师诊治。36%的患者在患者健康问卷-4 (PHQ- 4)中发现焦虑或抑郁呈阳性,11%的患者在DSM-5 (PC-PTSD-5)中发现创伤后应激障碍(PTSD)呈阳性。在亲自就诊的患者中,45%的患者有蒙特利尔认知评估(MOCA)确定的轻度或中度认知障碍。6分钟步行距离中位数预测为66%。预测FEV1、FVC和DLCO的中位数分别为86,80%和60%。61%的患者在住院前工作,91%的患者在住院前开车,只有22%和65%的患者分别回到了这些活动中。34例(56%)患者至少进行了一次转诊,有些患者接受了多达6次转诊。结论:在picc的ICU幸存者中发现了高患病率的PICS和社交障碍。结合跨学科的团队方法和标准化的调查是必要的,以认识到这些损害,以支持恢复到最佳状态可能。
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